UNITED STATES
                       SECURITIES AND EXCHANGE COMMISSION

                             Washington, D.C. 20549

                                    FORM 8-K




                                 CURRENT REPORT



                     Pursuant to Section 13 or 15(d) of the
                         Securities Exchange Act of 1934


       Date of Report (Date of Earliest Event Reported): November 10, 2004


                                    XOMA LTD.
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             (Exact name of registrant as specified in its charter)


                                     BERMUDA
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                 (State or other jurisdiction of incorporation)


              0-14710                                  52-2154066
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     (Commission File Number)               (IRS Employer Identification No.)

2910 Seventh Street, Berkeley, California                     94710
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(Address of principal executive offices)                   (Zip code)

Registrant's telephone number, including area code        (510) 204-7200
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          (Former name or former address, if changed since last report)





Item 1.01.  Entry into a Material Definitive Agreement

     As announced on November 10, 2004, XOMA Ltd. has entered into an exclusive
worldwide licensing agreement with Zephyr Sciences Inc.

     A copy of the press release is attached hereto as Exhibit 1 and is
incorporated herein by reference.

Item 9.01.  Exhibits

1. Press Release dated November 10, 2004.







                                    SIGNATURE

     Pursuant to the requirements of the Securities Exchange Act of 1934, the
registrant has duly caused this report to be signed on its behalf by the
undersigned hereunto duly authorized.

Dated:  November 10, 2004              XOMA LTD.




                                       By:  /s/  Christopher J. Margolin
                                            ---------------------------------
                                            Christopher J. Margolin
                                            Vice President, General
                                            Counsel and Secretary








                                  EXHIBIT INDEX


Number   Description
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1. Press Release dated November 10, 2004.