Exhibit
23.1
CONSENT
OF INDEPENDENT REGISTERED PUBLIC ACCOUNTING FIRM
We consent to the incorporation by
reference in the Registration Statement (Form S-8) pertaining to the XOMA Ltd.
1981 Share Option Plan, the XOMA Ltd. Restricted Share Plan, the XOMA Ltd. 2007
CEO Share Option Plan and the XOMA Ltd. 1992 Directors Share Option Plan of our
reports dated March 10, 2008, with respect to the consolidated financial
statements of XOMA Ltd. included in its Annual Report (Form 10-K) for the year
ended December 31, 2007, and the effectiveness of internal control over
financial reporting of XOMA Ltd., filed with the Securities and Exchange
Commission.
/s/ ERNST & YOUNG
LLP
Palo Alto,
California
June 2, 2008