Quarterly report pursuant to Section 13 or 15(d)

Subsequent Events - Additional Information (Details)

v3.19.1
Subsequent Events - Additional Information (Details) - Subsequent Events [Member]
$ in Millions
Apr. 07, 2019
USD ($)
Number
Aronora [Member]  
Subsequent Event [Line Items]  
Percentage of future developmental regulatory and sales milestones reduced 5
Aronora [Member] | Bayer Licensed Products [Member]  
Subsequent Event [Line Items]  
Percentage of future developmental regulatory and sales milestones 10
Aronora [Member] | Non Bayer Licensed Products [Member]  
Subsequent Event [Line Items]  
Percentage of future developmental regulatory and sales milestones 10
Aronora [Member] | Royalty Purchase Agreement [Member]  
Subsequent Event [Line Items]  
Number of hematology drug products in development | Number 5
Number of anti thrombotic candidates | Number 3
Initial amount payable $ 6.0
Additional amount payable $ 1.0
Agreement termination notice period 90 days
Received cumulative royalties on net sales per product amount $ 250.0
Milestones payments to aggregate amount of per product $ 85.0
Agreement termination period 6 months
Aronora [Member] | Royalty Purchase Agreement [Member] | Maximum [Member]  
Subsequent Event [Line Items]  
Additional amount payable $ 3.0
Aronora [Member] | Royalty Purchase Agreement [Member] | Bayer Licensed Products [Member]  
Subsequent Event [Line Items]  
Number of anti thrombotic candidates subject to option by bayer | Number 1
Aronora [Member] | Royalty Purchase Agreement [Member] | Non Bayer Licensed Products [Member]  
Subsequent Event [Line Items]  
Number of aditional early clinical hematology candidates | Number 2