Quarterly report pursuant to Section 13 or 15(d)

Stock-based Compensation (Tables)

v3.2.0.727
Stock-based Compensation (Tables)
6 Months Ended
Jun. 30, 2015
Stock-based Compensation [Abstract]  
Weighted average assumptions
The fair value of the stock options granted during the three and six months ended June 30, 2015 and 2014, was estimated based on the following weighted average assumptions:

   
Three Months Ended June 30,
   
Six Months Ended June 30,
 
   
2015
   
2014
   
2015
   
2014
 
Dividend yield
   
0
%
   
0
%
   
0
%
   
0
%
Expected volatility
   
81
%
   
91
%
   
82
%
   
93
%
Risk-free interest rate
   
1.65
%
   
1.68
%
   
1.40
%
   
1.71
%
Expected term
 
5.6 years
   
5.6 years
   
5.6 years
   
5.6 years
 
Stock option activity
Stock option activity for the six months ended June 30, 2015, was as follows:

   
Options
   
Weighted Average Exercise Price Per Share
   
Weighted Average Remaining Contractual Life
(in years)
   
Aggregate
Intrinsic
Value
(in thousands)
 
Outstanding at January 1, 2015
   
7,702,309
   
$
8.15
   
   
 
Granted
   
1,636,639
     
3.74
   
   
 
Exercised
   
(104,438
)
   
1.54
   
   
 
Forfeited, expired or cancelled
   
(771,854
)
   
21.84
   
   
 
Outstanding at June 30, 2015
   
8,462,656
   
$
6.13
     
7.24
   
$
4,107
 
Vested and expected to vest at June 30, 2015
   
8,118,591
   
$
6.20
     
7.16
   
$
4,054
 
Exercisable at June 30, 2015
   
5,172,965
   
$
7.15
     
6.20
   
$
3,179
 
Unvested RSU activity
Unvested RSU activity for the six months ended June 30, 2015, is summarized below:

   
Number of
Shares
   
Weighted-
Average Grant-
Date Fair Value
 
Unvested balance at January 1, 2015
   
1,953,879
   
$
5.46
 
Granted
   
1,586,017
     
3.78
 
Vested
   
(881,832
)
   
4.86
 
Forfeited
   
139,308
     
4.54
 
Unvested balance at June 30, 2015
   
2,797,372
   
$
4.65
 
Stock-based compensation expense
The following table shows total stock-based compensation expense included in the condensed consolidated statements of comprehensive loss for the three and six months ended June 30, 2015 and 2014 (in thousands): 

   
Three Months Ended June 30
   
Six Months Ended June 30,
 
   
2015
   
2014
   
2015
   
2014
 
Research and development
 
$
1,399
   
$
953
   
$
3,595
   
$
3,359
 
Selling, general and administrative
   
1,290
     
1,471
     
2,759
     
2,989
 
Total stock-based compensation expense
 
$
2,689
   
$
2,424
   
$
6,354
   
$
6,348