Quarterly report pursuant to Section 13 or 15(d)

Long-Term Debt and Other Financings - Novartis Note (Details)

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Long-Term Debt and Other Financings - Novartis Note (Details) - USD ($)
$ in Thousands
1 Months Ended
May 31, 2005
Mar. 31, 2020
Dec. 31, 2019
Sep. 30, 2015
Long-term debt        
Debt amount   $ 31,531    
Novartis Note        
Long-term debt        
Research and development expenses funded through loan facility, maximum (as a percent) 75.00%      
Maximum borrowing capacity under loan agreement $ 50,000      
Interest rate at period end (as a percent)   4.70%    
Amount by which note will be reduced upon achievement of specified milestones       $ 7,300
Debt amount   $ 15,900 $ 15,900  
Novartis Note | Six-month LIBOR        
Long-term debt        
Basis spread on variable rate 2.00%