Quarterly report pursuant to Section 13 or 15(d)

Long-Term Debt - Servier Loan Agreement - Additional Information (Details)

v3.7.0.1
Long-Term Debt - Servier Loan Agreement - Additional Information (Details)
1 Months Ended 3 Months Ended 6 Months Ended
Jan. 09, 2015
USD ($)
Tranche
Jan. 31, 2017
USD ($)
Jan. 31, 2016
EUR (€)
Jan. 31, 2011
USD ($)
Mar. 31, 2017
USD ($)
€ / $
Mar. 31, 2016
USD ($)
Jul. 31, 2017
Jan. 31, 2017
USD ($)
Mar. 31, 2017
EUR (€)
€ / $
Jan. 31, 2017
EUR (€)
Dec. 31, 2016
USD ($)
€ / $
Jan. 09, 2015
EUR (€)
Tranche
Debt Instrument [Line Items]                        
Accrued interest paid         $ 396,000 $ 646,000            
Carrying value of the loan         $ 26,629,000              
Servier Loan [Member]                        
Debt Instrument [Line Items]                        
Date of agreement         Dec. 30, 2010              
Maximum borrowing capacity under loan agreement | €                 € 15,000,000      
Proceeds from loan       $ 19,500,000                
Date of loan amendment         Jan. 09, 2015              
Date of agreement, after amendment         Aug. 12, 2013              
Number of tranches | Tranche 3                     3
Principal payment amount | €     € 3,000,000                  
Accrued interest paid | €     € 200,000                  
Unamortized discount on debt $ 1,900,000     $ 8,900,000                
Amortization of debt discount         $ 100,000 200,000            
Carrying value of the loan         12,544,000           $ 12,231,000  
Unrealized foreign exchange gains (loss) related to re-measurement of loan discount         6,000 38,000            
Outstanding principal balance         $ 12,800,000           $ 12,600,000  
Euro to US Dollar exchange rates | € / $         1.068       1.068   1.052  
Unrealized foreign exchange gains (loss) related to re-measurement of loan         $ (200,000) $ (500,000)            
Servier Loan [Member] | Tranche One [Member]                        
Debt Instrument [Line Items]                        
Maturity date Jan. 15, 2016                      
Principal payment amount | €                       € 3,000,000
Servier Loan [Member] | Tranche Two [Member]                        
Debt Instrument [Line Items]                        
Maturity date Jan. 15, 2017                      
Principal payment amount | €                       5,000,000
Servier Loan [Member] | Tranche Three [Member]                        
Debt Instrument [Line Items]                        
Maturity date Jan. 15, 2018                      
Principal payment amount | €                       € 7,000,000
Servier Loan [Member] | Mid-July 2016 Through Mid-January 2017 [Member]                        
Debt Instrument [Line Items]                        
Period of interest resetting               6 months        
Interest rate during period               1.81%        
Servier Loan [Member] | Amendment No.3 [Member] | Tranche Two [Member]                        
Debt Instrument [Line Items]                        
Maturity date   Jul. 15, 2017                    
Principal payment amount | €                   € 5,000,000    
Unamortized discount on debt   $ 400,000           $ 400,000        
Servier Loan [Member] | Forecast [Member] | Mid-January 2017 Through Mid-July 2017 [Member]                        
Debt Instrument [Line Items]                        
Period of interest resetting             6 months          
Interest rate during period             1.77%