Annual report pursuant to Section 13 and 15(d)
Cover
Document and Entity Information
Financial Statements
CONSOLIDATED BALANCE SHEETS
CONSOLIDATED BALANCE SHEETS (Parenthetical)
CONSOLIDATED STATEMENTS OF OPERATIONS AND COMPREHENSIVE LOSS
CONSOLIDATED STATEMENTS OF STOCKHOLDERS' EQUITY
CONSOLIDATED STATEMENTS OF CASH FLOWS
Notes to Financial Statements
Description of Business
Basis of Presentation and Significant Accounting Policies
Consolidated Financial Statements Details
Licensing and Other Arrangements
Royalty and Commercial Payment Purchase Agreements
Fair Value Measurements
Lease Agreement
Long-Term Debt
Income Taxes
Stock Based Compensation and Other Benefit Plans
Net Loss Per Share Attributable to Common Stockholders
Capital Stock
Commitments and Contingencies
Concentration of Risk, Segment and Geographic Information
Subsequent Events
Accounting Policies
Basis of Presentation and Significant Accounting Policies (Policies)
Notes Tables
Basis of Presentation and Significant Accounting Policies (Tables)
Consolidated Financial Statements Details (Tables)
Royalty and Commercial Payment Purchase Agreements (Tables)
Fair Value Measurements (Tables)
Lease Agreement (Tables)
Long-Term Debt (Tables)
Income Taxes (Tables)
Stock Based Compensation and Other Benefit Plans (Tables)
Net Loss Per Share Attributable to Common Stockholders (Tables)
Capital Stock (Tables)
Concentration of Risk, Segment and Geographic Information (Tables)
Notes Details
Description of Business - Liquidity (Details)
Basis of Presentation and Significant Accounting Policies - Unrestricted and Restricted Cash and Cash Equivalents (Details)
Basis of Presentation and Significant Accounting Policies - Intangible Assets (Details)
Consolidated Financial Statements Details - Equity Securities (Details)
Consolidated Financial Statements Details - Intangible Assets, Net (Details)
Consolidated Financial Statements Details - Accrued and Other Liabilities (Details)
Condensed Consolidated Financial Statements Details - Arbitration Proceeding (Details)
Licensing and Other Arrangements - Takeda (Details)
Licensing and Other Arrangements - Rezolute (Details)
Licensing and Other Arrangements - Janssen (Details)
Licensing and Other Arrangements - ObsEva (Details)
Licensing and Other Arrangements - Novartis - NIS793 (Details)
Licensing and Other Arrangements - Novartis - VPM087 (Details)
Licensing and Other Arrangements - Sale of Future Revenue Streams (Details)
Royalty and Commercial Payment Purchase Agreements - Summary (Details)
Royalty and Commercial Payment Purchase Agreements - LadRx (Details)
Royalty and Commercial Payment Purchase Agreements - Aptevo (Details)
Royalty and Commercial Payment Purchase Agreements - Agenus (Details)
Royalty and Commercial Payment Purchase Agreements - Bioasis (Details)
Royalty and Commercial Payment Purchase Agreements - Aronora (Details)
Royalty and Commercial Payment Purchase Agreements - Palo (Details)
Royalty and Commercial Payment Purchase Agreements - Viracta (Details)
Royalty and Commercial Payment Purchase Agreements - Kuros (Details)
Royalty and Commercial Payment Purchase Agreements - Affitech (Details)
Royalty and Commercial Payment Purchase Agreements - Summary of Royalty Receivable Activities (Details)
Fair Value Measurements - Financial Assets and Liabilities Carried at Fair Value on Recurring Basis (Details)
Fair Value Measurements - Equity Securities (Details)
Fair Value Measurements - Contingent Consideration (Details)
Lease Agreement - Leased facilities (Details)
Lease Agreement - Maturity of lease liabilities (Details)
Lease Agreement - Lease costs (Details)
Lease Agreement - Additional information (Details)
Long-Term Debt (Details)
Long-Term Debt - Summary of long-term debt (Details)
Long-Term Debt - Aggregate projected future principal and discounts (Details)
Long-Term Debt - Interest expense (Details)
Income Taxes - Provision for Income Taxes (Details)
Income Taxes - Reconciliation between statutory rate and effective rate (Details)
Income Taxes - Components of Net Deferred Tax Assets (Details)
Income Taxes - NOL (Details)
Income Taxes - Tax credit carryforward (Details)
Income Taxes - Unrecognized Tax Benefits (Details)
Stock Based Compensation and Other Benefit Plans - ESPP (Details)
Stock Based Compensation and Other Benefit Plans - Deferred Savings Plan (Details)
Stock Based Compensation and Other Benefit Plans - 2010 Plan Stock Options (Details)
Stock Based Compensation and Other Benefit Plans - FV Assumptions 2010 Plan Stock Options (Details)
Stock Based Compensation and Other Benefit Plans - Stock Option Inducement Awards (Details)
Stock Based Compensation and Other Benefit Plans - Stock Option Activity (Details)
Stock Based Compensation and Other Benefit Plans - Performance Stock Unit Awards (Details)
Stock Based Compensation and Other Benefit Plans - Performance Stock Unit Awards Fair Value (Details)
Stock Based Compensation and Other Benefit Plans - Performance Stock Unit Awards Activity (Details)
Stock Based Compensation and Other Benefit Plans - Stock-based Compensation Expense (Details)
Stock Based Compensation and Other Benefit Plans - Equity Awards Modification (Details)
Stock Based Compensation and Other Benefit Plans - Employee Retention Bonus (Details)
Stock Based Compensation and Other Benefit Plans - CEO Departure and Continuity Incentive (Details)
Net Loss Per Share Attributable to Common Stockholders - Outstanding Securities Considered Anti-Dilutive (Details)
Net Loss Per Share Attributable to Common Stockholders - Reconciliation of Numerator and Denominator Used in Calculation of EPS (Details)
Capital Stock - Series X and Series Y Convertible Preferred Stock (Details)
Capital Stock - Series A Preferred Stock (Details)
Capital Stock - Depositary Shares Representing Interest in Series B Preferred Stock (Details)
Capital Stock - Dividends (Details)
Capital Stock - BVF Ownership (Details)
Capital Stock - ATM Agreements (Details)
Capital Stock - Summary of Common Stock Warrants Outstanding (Details)
Capital Stock - Common Stock Warrants (Details)
Capital Stock - Weighted average assumptions (Details)
Commitments and Contingencies - Collaborative Agreements, Royalties and Milestone Payments (Details)
Commitments and Contingencies - Contingent Consideration (Details)
Commitments and Contingencies - Arbitration Proceeding (Details)
Concentration of Risk, Segment and Geographic Information - Concentration of Risk (Details)
Concentration of Risk, Segment and Geographic Information - Segment Information (Details)
Concentration of Risk, Segment and Geographic Information - Revenue by Geographical Region (Details)
Subsequent Events (Details)
Uncategorized
Pay vs Performance Disclosure
Insider Trading Arrangements
Document and Entity Information
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