Quarterly report pursuant to Section 13 or 15(d)

Subsequent Events - Additional Information (Details)

v3.10.0.1
Subsequent Events - Additional Information (Details)
$ in Millions
1 Months Ended
Apr. 14, 2018
USD ($)
Facility
Nov. 21, 2017
USD ($)
Facility
Oct. 31, 2018
USD ($)
Facility
Nov. 30, 2018
USD ($)
Subsequent Event [Line Items]        
Operating leases, number of portions of leased facilities | Facility 1 1    
Operating leases, number of leased facilities | Facility 3 3    
Operating leases, sublease commencement date May 01, 2018 Dec. 26, 2017    
Operating leases sublease income receivable | $ $ 1.1 $ 5.1    
Operating leases sublease expiry date 2023-04 2023-04    
Forecast [Member] | Maximum [Member] | BVF [Member]        
Subsequent Event [Line Items]        
Amount of securities agreed to sold in rights offering | $       $ 20.0
Forecast [Member] | Holders of Common Stock and Series X Preferred Stock [Member] | Maximum [Member]        
Subsequent Event [Line Items]        
Rights offring amount | $       $ 20.0
Subsequent Event [Member]        
Subsequent Event [Line Items]        
Operating leases, number of portions of leased facilities | Facility     1  
Operating leases, number of leased facilities | Facility     3  
Operating leases, sublease commencement date     Oct. 24, 2018  
Operating leases sublease income receivable | $     $ 1.7  
Operating leases sublease expiry date     2021-05