Annual report pursuant to Section 13 and 15(d)

Income Taxes (Details)

v2.4.1.9
Income Taxes (Details) (USD $)
3 Months Ended 12 Months Ended
Dec. 31, 2014
Sep. 30, 2014
Jun. 30, 2014
Mar. 31, 2014
Dec. 31, 2013
Sep. 30, 2013
Jun. 30, 2013
Mar. 31, 2013
Dec. 31, 2014
Dec. 31, 2013
Dec. 31, 2012
Components of Income Tax Expense (Benefit), Continuing Operations [Abstract]                      
Federal income tax (benefit) provision                 $ 0us-gaap_FederalIncomeTaxExpenseBenefitContinuingOperations $ (14,000)us-gaap_FederalIncomeTaxExpenseBenefitContinuingOperations $ (74,000)us-gaap_FederalIncomeTaxExpenseBenefitContinuingOperations
Total 0us-gaap_IncomeTaxExpenseBenefit 0us-gaap_IncomeTaxExpenseBenefit 0us-gaap_IncomeTaxExpenseBenefit 0us-gaap_IncomeTaxExpenseBenefit 1,000us-gaap_IncomeTaxExpenseBenefit (15,000)us-gaap_IncomeTaxExpenseBenefit 0us-gaap_IncomeTaxExpenseBenefit 0us-gaap_IncomeTaxExpenseBenefit 0us-gaap_IncomeTaxExpenseBenefit (14,000)us-gaap_IncomeTaxExpenseBenefit (74,000)us-gaap_IncomeTaxExpenseBenefit
Effective Income Tax Rate Reconciliation, Percent [Abstract]                      
Federal tax at statutory rate (in hundredths)                 34.00%us-gaap_EffectiveIncomeTaxRateReconciliationAtFederalStatutoryIncomeTaxRate 34.00%us-gaap_EffectiveIncomeTaxRateReconciliationAtFederalStatutoryIncomeTaxRate 34.00%us-gaap_EffectiveIncomeTaxRateReconciliationAtFederalStatutoryIncomeTaxRate
Warrant valuation (in hundredths)                 40.00%xoma_EffectiveIncomeTaxRateReconciliationWarrantValuationPercent (17.00%)xoma_EffectiveIncomeTaxRateReconciliationWarrantValuationPercent (4.00%)xoma_EffectiveIncomeTaxRateReconciliationWarrantValuationPercent
Permanent items and other (in hundredths)                 (1.00%)us-gaap_EffectiveIncomeTaxRateReconciliationOtherAdjustments 0.00%us-gaap_EffectiveIncomeTaxRateReconciliationOtherAdjustments (1.00%)us-gaap_EffectiveIncomeTaxRateReconciliationOtherAdjustments
Valuation allowance (in hundredths)                 (73.00%)us-gaap_EffectiveIncomeTaxRateReconciliationChangeInDeferredTaxAssetsValuationAllowance (17.00%)us-gaap_EffectiveIncomeTaxRateReconciliationChangeInDeferredTaxAssetsValuationAllowance (29.00%)us-gaap_EffectiveIncomeTaxRateReconciliationChangeInDeferredTaxAssetsValuationAllowance
Total (in hundredths)                 0.00%us-gaap_EffectiveIncomeTaxRateContinuingOperations 0.00%us-gaap_EffectiveIncomeTaxRateContinuingOperations 0.00%us-gaap_EffectiveIncomeTaxRateContinuingOperations
Significant components of net deferred tax assets [Abstract]                      
Capitalized research and development expenses 50,900,000us-gaap_DeferredTaxAssetsInProcessResearchAndDevelopment       49,400,000us-gaap_DeferredTaxAssetsInProcessResearchAndDevelopment       50,900,000us-gaap_DeferredTaxAssetsInProcessResearchAndDevelopment 49,400,000us-gaap_DeferredTaxAssetsInProcessResearchAndDevelopment  
Net operating loss carryforwards 105,000,000us-gaap_DeferredTaxAssetsOperatingLossCarryforwards       78,400,000us-gaap_DeferredTaxAssetsOperatingLossCarryforwards       105,000,000us-gaap_DeferredTaxAssetsOperatingLossCarryforwards 78,400,000us-gaap_DeferredTaxAssetsOperatingLossCarryforwards  
Research and development and other credit carryforwards 12,100,000us-gaap_DeferredTaxAssetsTaxCreditCarryforwards       8,800,000us-gaap_DeferredTaxAssetsTaxCreditCarryforwards       12,100,000us-gaap_DeferredTaxAssetsTaxCreditCarryforwards 8,800,000us-gaap_DeferredTaxAssetsTaxCreditCarryforwards  
Other 22,100,000us-gaap_DeferredTaxAssetsOther       23,500,000us-gaap_DeferredTaxAssetsOther       22,100,000us-gaap_DeferredTaxAssetsOther 23,500,000us-gaap_DeferredTaxAssetsOther  
Total deferred tax assets 190,100,000us-gaap_DeferredTaxAssetsGross       160,100,000us-gaap_DeferredTaxAssetsGross       190,100,000us-gaap_DeferredTaxAssetsGross 160,100,000us-gaap_DeferredTaxAssetsGross  
Valuation allowance (190,100,000)us-gaap_DeferredTaxAssetsValuationAllowance       (160,100,000)us-gaap_DeferredTaxAssetsValuationAllowance       (190,100,000)us-gaap_DeferredTaxAssetsValuationAllowance (160,100,000)us-gaap_DeferredTaxAssetsValuationAllowance  
Net deferred tax assets 0us-gaap_DeferredTaxAssetsNet       0us-gaap_DeferredTaxAssetsNet       0us-gaap_DeferredTaxAssetsNet 0us-gaap_DeferredTaxAssetsNet  
Increase (decrease) in the valuation allowance                 30,000,000us-gaap_ValuationAllowanceDeferredTaxAssetChangeInAmount (74,000,000)us-gaap_ValuationAllowanceDeferredTaxAssetChangeInAmount (6,000,000)us-gaap_ValuationAllowanceDeferredTaxAssetChangeInAmount
Unrecognized Tax Benefits [Roll Forward]                      
Beginning Balance       4,274,000us-gaap_UnrecognizedTaxBenefits       4,104,000us-gaap_UnrecognizedTaxBenefits 4,274,000us-gaap_UnrecognizedTaxBenefits 4,104,000us-gaap_UnrecognizedTaxBenefits 0us-gaap_UnrecognizedTaxBenefits
Increase related to current year tax position                 720,000us-gaap_UnrecognizedTaxBenefitsIncreasesResultingFromCurrentPeriodTaxPositions 164,000us-gaap_UnrecognizedTaxBenefitsIncreasesResultingFromCurrentPeriodTaxPositions 49,000us-gaap_UnrecognizedTaxBenefitsIncreasesResultingFromCurrentPeriodTaxPositions
Increase related to prior year tax position                 509,000us-gaap_UnrecognizedTaxBenefitsIncreasesResultingFromPriorPeriodTaxPositions 6,000us-gaap_UnrecognizedTaxBenefitsIncreasesResultingFromPriorPeriodTaxPositions 4,055,000us-gaap_UnrecognizedTaxBenefitsIncreasesResultingFromPriorPeriodTaxPositions
Ending Balance 5,503,000us-gaap_UnrecognizedTaxBenefits       4,274,000us-gaap_UnrecognizedTaxBenefits       5,503,000us-gaap_UnrecognizedTaxBenefits 4,274,000us-gaap_UnrecognizedTaxBenefits 4,104,000us-gaap_UnrecognizedTaxBenefits
Unrecognized Tax Benefits that Would Impact Effective Tax Rate 4,000,000us-gaap_UnrecognizedTaxBenefitsThatWouldImpactEffectiveTaxRate               4,000,000us-gaap_UnrecognizedTaxBenefitsThatWouldImpactEffectiveTaxRate    
Stock Option [Member]                      
Operating Loss Carryforwards [Line Items]                      
Net Operating Loss Carry-forwards 5,200,000us-gaap_OperatingLossCarryforwards
/ us-gaap_FinancialInstrumentAxis
= us-gaap_StockOptionMember
              5,200,000us-gaap_OperatingLossCarryforwards
/ us-gaap_FinancialInstrumentAxis
= us-gaap_StockOptionMember
   
State [Member]                      
Operating Loss Carryforwards [Line Items]                      
Net Operating Loss Carry-forwards 132,300,000us-gaap_OperatingLossCarryforwards
/ us-gaap_IncomeTaxAuthorityAxis
= us-gaap_StateAndLocalJurisdictionMember
              132,300,000us-gaap_OperatingLossCarryforwards
/ us-gaap_IncomeTaxAuthorityAxis
= us-gaap_StateAndLocalJurisdictionMember
   
California [Member]                      
Operating Loss Carryforwards [Line Items]                      
Net operating loss carry-forward expired                 54,300,000xoma_OperatingLossCarryforwardsExpirationDuringPeriod
/ us-gaap_IncomeTaxAuthorityAxis
= stpr_CA
16,800,000xoma_OperatingLossCarryforwardsExpirationDuringPeriod
/ us-gaap_IncomeTaxAuthorityAxis
= stpr_CA
10,400,000xoma_OperatingLossCarryforwardsExpirationDuringPeriod
/ us-gaap_IncomeTaxAuthorityAxis
= stpr_CA
Federal [Member]                      
Operating Loss Carryforwards [Line Items]                      
Net Operating Loss Carry-forwards 292,300,000us-gaap_OperatingLossCarryforwards
/ us-gaap_IncomeTaxAuthorityAxis
= us-gaap_InternalRevenueServiceIRSMember
              292,300,000us-gaap_OperatingLossCarryforwards
/ us-gaap_IncomeTaxAuthorityAxis
= us-gaap_InternalRevenueServiceIRSMember
   
Net operating loss carry-forward expired                 $ 0xoma_OperatingLossCarryforwardsExpirationDuringPeriod
/ us-gaap_IncomeTaxAuthorityAxis
= us-gaap_InternalRevenueServiceIRSMember
$ 0xoma_OperatingLossCarryforwardsExpirationDuringPeriod
/ us-gaap_IncomeTaxAuthorityAxis
= us-gaap_InternalRevenueServiceIRSMember
$ 0xoma_OperatingLossCarryforwardsExpirationDuringPeriod
/ us-gaap_IncomeTaxAuthorityAxis
= us-gaap_InternalRevenueServiceIRSMember