Quarterly report pursuant to Section 13 or 15(d)

Long-Term Debt - Silicon Valley Bank Loan Agreement - Additional Information (Details)

v3.10.0.1
Long-Term Debt - Silicon Valley Bank Loan Agreement - Additional Information (Details) - Loan and Security Agreement [Member] - Silicon Valley Bank [Member] - USD ($)
3 Months Ended
May 07, 2018
Jun. 30, 2018
Warrants for Common Stock [Member]    
Debt Instrument [Line Items]    
Aggregate number of shares of common stock called by warrants 6,332  
Exercise price of per share $ 23.69  
Exercisable period of warrants 10 years  
Fair value of warrant $ 100,000  
Debt issuance costs 200,000  
Term Loan [Member]    
Debt Instrument [Line Items]    
Maximum borrowing capacity under loan agreement 20,000,000  
Increase borrowing capacity under loan agreement $ 40,000,000  
Earlier effecitve date of term loan Mar. 31, 2019  
Effective date of term loan extended Mar. 31, 2020  
Gross cash proceeds received from milestone and licensing payments $ 20,000,000  
Basis spread on variable rate 4.75%  
Variable rate basis The interest-only period will be followed by equal monthly payments of principal and interest over 24 months. Each Term Loan Advance will mature at the earlier of (i) the 23 months following the applicable term loan amortization date for each such Term Loan Advance (ii) March 1, 2023, or (iii) 30 days prior to the earliest maturity of any portion of the Company’s loan with Novartis (the “Loan Maturity Date”). After repayment, no Term Loan Advance (or any portion thereof) may be reborrowed.  
Period of monthly payments of principal and interest 24 months  
Repayment of term loan $ 0  
Loan borrowed $ 0 $ 0
Percentage of final payment fee of Loan 8.50%  
Percentage of prepayment fee 3.00%  
Additional interest rate of outstanding payments due 4.00%  
Percentage of unused portion of term loan 1.00%  
Loan agreement description (i) the termination of the Loan Agreement, or (ii) the Draw Period if the aggregate original principal amount of the Term Loan Advances is less than $5.0 million.  
Outstanding term loan   0
Term Loan [Member] | Deferred Charge    
Debt Instrument [Line Items]    
Fair value of warrant   100,000
Debt issuance costs   200,000
Non-cash interest expense resulting from amortization   $ 12,000
Term Loan [Member] | Maximum [Member]    
Debt Instrument [Line Items]    
Aggregate original principal amount $ 5,000,000  
Term Loan [Member] | First Anniversary [Member]    
Debt Instrument [Line Items]    
Percentage of prepayment fee 2.00%  
Term Loan [Member] | Second Anniversary [Member]    
Debt Instrument [Line Items]    
Percentage of prepayment fee 1.00%  
Term Loan [Member] | Prime Rate [Member]    
Debt Instrument [Line Items]    
Basis spread on variable rate 0.25%  
Novartis [Member]    
Debt Instrument [Line Items]    
Maturity date Mar. 01, 2023  
Days of interest, period 30 days  
Earliest maturity of loan 30 days