Annual report pursuant to Section 13 and 15(d)

Collaborative, Licensing and Other Arrangements - Servier - Additional Information (Details)

v3.8.0.1
Collaborative, Licensing and Other Arrangements - Servier - Additional Information (Details) - Collaborative Arrangement [Member] - Servier [Member]
€ in Millions, $ in Millions
1 Months Ended 6 Months Ended 12 Months Ended
Jan. 31, 2011
USD ($)
Jan. 31, 2011
EUR (€)
Mar. 25, 2016
USD ($)
Dec. 31, 2016
USD ($)
Dec. 31, 2015
USD ($)
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]          
Upfront payment received $ 15.0        
Proceeds from loan $ 19.5 € 15.0      
Deferred revenue recognized     $ 0.6    
Contract and other revenue       $ 0.6 $ 1.2