Annual report pursuant to Section 13 and 15(d)

Dispositions - Additional Information (Details)

v3.8.0.1
Dispositions - Additional Information (Details) - USD ($)
 1 Months Ended 12 Months Ended
Dec. 31, 2015
Nov. 05, 2015
Nov. 04, 2015
Feb. 28, 2017
Dec. 31, 2017
Dec. 31, 2015
Income Statement Balance Sheet And Additional Disclosures By Disposal Groups Including Discontinued Operations [Line Items]            
Gain on sale of business           $ 3,505,000
Asset Purchase Agreement and Ology Bioservices License Agreement [Member]            
Income Statement Balance Sheet And Additional Disclosures By Disposal Groups Including Discontinued Operations [Line Items]            
Cash payments from Ology Bioservices       $ 4,500,000    
Number of shares removed from obligation to issue of common stock       23,008    
Contingent upon achieving certain specified future operating objectives       $ 3,000,000    
Amount entitled to receive         $ 4,600,000  
Amount received from sale of discontinued operation         2,200,000  
Remaining consideration amount receivable         2,400,000  
Remaining amount receivable in monthly installments         1,700,000  
Remaining amount receivable in quarterly installments         $ 700,000  
Biodefense Business [Member]            
Income Statement Balance Sheet And Additional Disclosures By Disposal Groups Including Discontinued Operations [Line Items]            
Sales of business, number of common stock shares eligible to receive     23,008      
Royalties receivable percentage on net sales     15.00%      
Biodefense Business [Member] | Maximum [Member]            
Income Statement Balance Sheet And Additional Disclosures By Disposal Groups Including Discontinued Operations [Line Items]            
Cash payments from Ology Bioservices     $ 4,500,000      
Manufacturing Facility in Berkeley, California [Member] | Agenus Purchase Agreement [Member]            
Income Statement Balance Sheet And Additional Disclosures By Disposal Groups Including Discontinued Operations [Line Items]            
Cash received from sale of business $ 4,700,000          
Sale of business, value of common stock shares received 500,000         500,000
Liabilities assumed $ 300,000          
Sales of business, number of common stock shares received 109,211          
Contingent consideration value of common stock to be received           500,000
Consideration received for employees who would not have otherwise been retained           200,000
Carrying value of business sold $ 2,200,000         2,200,000
Manufacturing Facility in Berkeley, California [Member] | Agenus Purchase Agreement [Member] | Other Income (Expense), Net [Member]            
Income Statement Balance Sheet And Additional Disclosures By Disposal Groups Including Discontinued Operations [Line Items]            
Gain on sale of business           $ 3,500,000
Manufacturing Facility in Berkeley, California [Member] | Maximum [Member] | Agenus Purchase Agreement [Member]            
Income Statement Balance Sheet And Additional Disclosures By Disposal Groups Including Discontinued Operations [Line Items]            
Cash received from sale of business   $ 5,000,000        
Sale of business, value of common stock shares received   $ 1,000,000