Quarterly report pursuant to Section 13 or 15(d)
Cover
Document and Entity Information
Financial Statements
CONDENSED CONSOLIDATED BALANCE SHEETS (unaudited)
CONDENSED CONSOLIDATED BALANCE SHEETS (unaudited) (Parenthetical)
CONDENSED CONSOLIDATED STATEMENTS OF COMPREHENSIVE LOSS (unaudited)
CONDENSED CONSOLIDATED STATEMENTS OF CASH FLOWS (unaudited)
Notes to Financial Statements
Description of Business
Basis of Presentation and Significant Accounting Policies
Condensed Consolidated Financial Statements Detail
Collaborative and Other Agreements
Fair Value Measurements
Restructuring Charges
Long-Term Debt and Other Financings
Legal Proceedings, Commitments and Contingencies
Stock-based Compensation
Subsequent Events
Accounting Policies
Basis of Presentation and Significant Accounting Policies (Policies)
Notes Tables
Basis of Presentation and Significant Accounting Policies (Tables)
Condensed Consolidated Financial Statements Detail (Tables)
Fair Value Measurements (Tables)
Restructuring Charges (Tables)
Long-Term Debt and Other Financings (Tables)
Stock-based Compensation (Tables)
Notes Details
Description of Business - Additional Information (Details)
Basis of Presentation and Significant Accounting Policies - Additional Information 1 (Details)
Basis of Presentation and Significant Accounting Policies - Additional Information 2 (Details)
Basis of Presentation and Significant Accounting Policies - Impact of Early Adoption on the Condensed Consolidated Balance Sheets (Details)
Condensed Consolidated Financial Statements Detail - Outstanding securities considered anti-dilutive (Details)
Condensed Consolidated Financial Statements Detail - Reconciliation of the numerators and denominators of the basic and diluted net loss per share of common stock (Details)
Condensed Consolidated Financial Statements Detail - Additional Information 1 (Details)
Condensed Consolidated Financial Statements Detail - Accrued and other liabilities (Details)
Condensed Consolidated Financial Statements Detail - Additional Information 2 (Details)
Collaborative and Other Agreements - Additional Information (Details)
Fair Value Measurements - Financial Assets and Liabilities Carried At Fair Value on Recurring Basis (Details)
Fair Value Measurements - Additional Information (Details)
Fair Value Measurements - Warrant Liabilities, Fair Value Assumptions (Details)
Fair Value Measurements - Summary of Changes in Fair Value of Level 3 Financial Liabilities (Details)
Fair Value Measurements - Outstanding Debt Carrying Amount and Estimated Fair Value (Details)
Restructuring Charges - Additional Information (Details)
Restructuring Charges (Details)
Long-Term Debt and Other Financings - Novartis Note - Additional Information (Details)
Long-Term Debt and Other Financings - Servier Loan Agreement - Additional Information (Details)
Long-Term Debt and Other Financings - General Electric Capital Corporation (GECC) Term Loan - Additional Information (Details)
Long-Term Debt and Other Financings - Hercules Term Loan - Additional Information (Details)
Long-Term Debt and Other Financings - Aggregate Future Principal and Final Fee Payments of Interest Bearing Obligations (Details)
Long-Term Debt and Other Financings - Interest Expense and Amortization of Debt Issuance Costs (Details)
Legal Proceedings, Commitments and Contingencies - Additional Information (Details)
Stock-based Compensation - Additional Information (Details)
Stock-based Compensation - Weighted Average Assumptions (Details)
Stock-based Compensation - Stock Option Activity (Details)
Stock-based Compensation - Unvested RSU Activity (Details)
Stock-based Compensation - Stock-based Compensation Expense (Details)
Subsequent Events (Details)
Stock-based Compensation - Stock-based Compensation Expense (Details)