Annual report pursuant to Section 13 and 15(d)

CONSOLIDATED STATEMENTS OF STOCKHOLDERS' (DEFICIT) EQUITY

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CONSOLIDATED STATEMENTS OF STOCKHOLDERS' (DEFICIT) EQUITY - USD ($)
shares in Thousands, $ in Thousands
Total
Common Stock [Member]
Paid-In Capital [Member]
Accumulated Comprehensive Income [Member]
Accumulated Deficit [Member]
Balance at Dec. 31, 2012 $ 21,467 $ 615 $ 977,962 $ 8 $ (957,118)
Balance (in shares) at Dec. 31, 2012   82,447      
Increase (Decrease) in Stockholders' Equity [Roll Forward]          
Exercise of stock options, contributions to 401(k) and incentive plans 2,220 $ 7 2,213    
Exercise of stock options, contributions to 401(k) and incentive plans (in shares)   933      
Vesting of restricted stock units   $ 6 (6)    
Vesting of restricted stock units (in shares)   801      
Stock-based compensation expense 5,099   5,099    
Sale of shares of common stock 82,946 $ 147 82,799    
Sale of shares of common stock (in shares)   19,661      
Exercise of warrants 8,348 $ 12 8,336    
Exercise of warrants (in shares)   1,544      
Net loss (124,058)       (124,058)
Other comprehensive income (loss) (9)     (9)  
Balance at Dec. 31, 2013 (3,987) $ 787 1,076,403 (1) (1,081,176)
Balance (in shares) at Dec. 31, 2013   105,386      
Increase (Decrease) in Stockholders' Equity [Roll Forward]          
Exercise of stock options, contributions to 401(k) and incentive plans 4,526 $ 11 4,515    
Exercise of stock options, contributions to 401(k) and incentive plans (in shares)   1,065      
Vesting of restricted stock units   $ 7 (7)    
Vesting of restricted stock units (in shares)   981      
Stock-based compensation expense 10,772   10,772    
Sale of shares of common stock 37,786 $ 61 37,725    
Sale of shares of common stock (in shares)   8,097      
Issuance of warrants (10,258)   (10,258)    
Exercise of warrants 2,560 $ 3 2,557    
Exercise of warrants (in shares)   363      
Net loss (38,301)       (38,301)
Other comprehensive income (loss) 1     $ 1  
Balance at Dec. 31, 2014 3,099 $ 869 1,121,707   (1,119,477)
Balance (in shares) at Dec. 31, 2014   115,892      
Increase (Decrease) in Stockholders' Equity [Roll Forward]          
Exercise of stock options, contributions to 401(k) and incentive plans 1,467 $ 4 1,463    
Exercise of stock options, contributions to 401(k) and incentive plans (in shares)   542      
Vesting of restricted stock units   $ 9 (9)    
Vesting of restricted stock units (in shares)   1,202      
Stock-based compensation expense 9,727   9,727    
Issuance of warrants 450   450    
Exercise of warrants 3,554 $ 11 3,543    
Exercise of warrants (in shares)   1,410      
Net loss (20,606)       (20,606)
Balance at Dec. 31, 2015 $ (2,309) $ 893 $ 1,136,881   $ (1,140,083)
Balance (in shares) at Dec. 31, 2015   119,046