Annual report pursuant to Section 13 and 15(d)

Collaborative, Licensing and Other Arrangements - Servier - Additional Information (Details)

v3.3.1.900
Collaborative, Licensing and Other Arrangements - Servier - Additional Information (Details)
$ in Thousands, € in Millions
 1 Months Ended 12 Months Ended
Jan. 31, 2011
USD ($)
Jan. 31, 2011
EUR (€)
Dec. 31, 2015
USD ($)
Dec. 31, 2015
EUR (€)
Dec. 31, 2014
USD ($)
Dec. 31, 2013
USD ($)
Dec. 31, 2011
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]              
Deferred revenue – current     $ 3,198   $ 1,089    
Collaborative Arrangement [Member] | Servier [Member]              
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]              
Upfront payment received $ 15,000            
Period for recognizing deferred revenue             8 months
Proceeds from loan $ 19,500 € 15.0          
Future initial research and development expenses to be funded by counterparty     50,000        
Contract and other revenue     1,200   $ 3,500 $ 13,600  
Eligible milestone payments receivable | €       € 356.5      
Eligible milestone payments receivable under specific rights not met | €       633.8      
Eligible milestone payments receivable, after amendment | €       341.5      
Eligible milestone payments receivable under specific rights not met, after amendment | €       € 618.8      
Deferred revenue – current     $ 600