Annual report pursuant to Section 13 and 15(d)

Long-Term Debt and Other Financings - Servier Loan Agreement - Additional Information (Details)

v3.10.0.1
Long-Term Debt and Other Financings - Servier Loan Agreement - Additional Information (Details)
1 Months Ended 12 Months Ended
Aug. 25, 2017
USD ($)
€ / $
Dec. 31, 2010
USD ($)
Dec. 31, 2017
USD ($)
Dec. 31, 2010
EUR (€)
Debt Instrument [Line Items]        
Loss on extinguishment of debt     $ 650,000  
Servier Loan [Member]        
Debt Instrument [Line Items]        
Date of agreement   Dec. 31, 2010    
Borrowing capacity under loan agreement   $ 19,500,000   € 15,000,000
Payment of debt through cash by NIBR $ 14,300,000      
Euro to US Dollar exchange rates | € / $ 1.1932      
Loss on extinguishment of debt     $ 100,000