Annual report pursuant to Section 13 and 15(d)

Compensation and Other Benefit Plans - Stock-based Compensation Expense (Details)

v3.10.0.1
Compensation and Other Benefit Plans - Stock-based Compensation Expense (Details) - USD ($)
$ in Thousands
12 Months Ended
Dec. 31, 2018
Dec. 31, 2017
Employee Service Share-based Compensation, Allocation of Recognized Period Costs [Line Items]    
Total stock-based compensation expense $ 3,902 $ 7,301
Research and Development [Member]    
Employee Service Share-based Compensation, Allocation of Recognized Period Costs [Line Items]    
Total stock-based compensation expense 369 876
General and Administrative [Member]    
Employee Service Share-based Compensation, Allocation of Recognized Period Costs [Line Items]    
Total stock-based compensation expense $ 3,533 $ 6,425