Annual report pursuant to Section 13 and 15(d)

Long-Term Debt and Other Financings - Hercules Term Loan - Additional Information (Details)

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Long-Term Debt and Other Financings - Hercules Term Loan - Additional Information (Details) - USD ($)
$ / shares in Units, $ in Thousands
12 Months Ended
Mar. 21, 2017
Feb. 27, 2015
Dec. 31, 2017
Debt Instrument [Line Items]      
Loss on extinguishment of debt     $ 650
Hercules Term Loan [Member]      
Debt Instrument [Line Items]      
Prepayment charge not required to pay 1.00%    
Loss on extinguishment of debt     $ 500
Aggregate number of unregistered shares of common stock called by warrants (in shares)   9,063  
Exercise price of warrants (in dollars per share)   $ 66.20  
Exercisable period of warrants   5 years  
Warrants expiration period   2020-02