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Compensation and Other Benefit Plans (Details) (USD $)
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12 Months Ended | 3 Months Ended | 12 Months Ended | 12 Months Ended | 3 Months Ended | 12 Months Ended | ||||||||||||||||||||||||||||||
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Dec. 31, 2013
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Dec. 31, 2012
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Dec. 31, 2011
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Dec. 31, 2013
Research and Development [Member]
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Dec. 31, 2012
Research and Development [Member]
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Dec. 31, 2011
Research and Development [Member]
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Dec. 31, 2013
Selling, General and Administrative [Member]
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Dec. 31, 2012
Selling, General and Administrative [Member]
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Dec. 31, 2011
Selling, General and Administrative [Member]
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Dec. 31, 2013
Maximum [Member]
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Dec. 31, 2013
Stock Options [Member]
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Dec. 31, 2012
Stock Options [Member]
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Dec. 31, 2011
Stock Options [Member]
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Dec. 31, 2013
Stock Options [Member]
Directors [Member]
Minimum [Member]
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Dec. 31, 2013
Stock Options [Member]
Directors [Member]
Maximum [Member]
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Sep. 30, 2011
Stock Options [Member]
Chief Executive Officer [Member]
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Dec. 31, 2013
Restricted Stock Units (RSUs) [Member]
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Dec. 31, 2012
Restricted Stock Units (RSUs) [Member]
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Dec. 31, 2011
Restricted Stock Units (RSUs) [Member]
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Dec. 31, 2013
Employee Stock Purchase Plan [Member]
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Dec. 31, 2012
Employee Stock Purchase Plan [Member]
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Dec. 31, 2011
Employee Stock Purchase Plan [Member]
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Dec. 31, 2013
Employee Stock Purchase Plan [Member]
Maximum [Member]
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Dec. 31, 2013
Long Term Incentive Plan [Member]
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Dec. 31, 2011
Long Term Incentive Plan [Member]
Stock Options [Member]
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Dec. 31, 2013
Long Term Incentive Plan [Member]
Stock Options [Member]
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Dec. 31, 2012
Long Term Incentive Plan [Member]
Stock Options [Member]
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Dec. 31, 2013
Long Term Incentive Plan [Member]
Stock Options [Member]
Directors [Member]
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Dec. 31, 2012
Long Term Incentive Plan [Member]
Stock Options [Member]
Directors [Member]
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Dec. 31, 2013
Long Term Incentive Plan [Member]
Stock Options [Member]
Non-Executive Employees [Member]
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Dec. 31, 2012
Long Term Incentive Plan [Member]
Stock Options [Member]
Non-Executive Employees [Member]
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| Share-based Compensation Arrangement by Share-based Payment Award [Line Items] | ||||||||||||||||||||||||||||||||||||
| Vesting period | 4 years | 1 year | 3 years | 3 years | 3 years | 3 years | 2 years | 1 year | 1 year | 4 years | 4 years | |||||||||||||||||||||||||
| Expiration period | ten years from the date of the grant or three months from the date of termination of employment (longer in case of death or certain retirements). | ten years from the date of the grant or three to six months from the date of termination of employment (longer in case of death or certain retirements). | ||||||||||||||||||||||||||||||||||
| Purchase price to acquire shares (in hundredths) | 95.00% | |||||||||||||||||||||||||||||||||||
| Shares authorized for issuance (in shares) | 233,333 | 15,754,331 | ||||||||||||||||||||||||||||||||||
| Employee compensation available for share purchases, maximum (in hundredths) | 15.00% | |||||||||||||||||||||||||||||||||||
| Shares purchased (in shares) | 15,262 | 17,054 | 30,044 | |||||||||||||||||||||||||||||||||
| Net payroll deductions to acquire shares | $ 60,000 | $ 46,000 | $ 54,000 | |||||||||||||||||||||||||||||||||
| Stock-based compensation charge | 700,000 | |||||||||||||||||||||||||||||||||||
| Deferred savings plan [Abstract] | ||||||||||||||||||||||||||||||||||||
| Maximum annual contribution per employee (in hundredths) | 50.00% | |||||||||||||||||||||||||||||||||||
| Maximum annual contribution per employee | 17,500 | |||||||||||||||||||||||||||||||||||
| Maximum annual contribution per employee over 50 years old | 23,000 | |||||||||||||||||||||||||||||||||||
| Age requirement for participant to be eligible for a catch-up contribution, minimum | 50 years | |||||||||||||||||||||||||||||||||||
| Employer matching contribution percentage, maximum (in hundredths) | 50.00% | |||||||||||||||||||||||||||||||||||
| Deferred savings plan expense | 900,000 | 800,000 | 1,100,000 | |||||||||||||||||||||||||||||||||
| Deferred savings plan expense paid in common shares (in hundredths) | 100.00% | 100.00% | 100.00% | |||||||||||||||||||||||||||||||||
| Number of shares of common stock to be issued upon exercise of options outstanding (in shares) | 9,184,913 | |||||||||||||||||||||||||||||||||||
| Stock option activity [Roll Forward] | ||||||||||||||||||||||||||||||||||||
| Outstanding at beginning of year (in shares) | 6,788,383 | 5,053,435 | 2,331,450 | |||||||||||||||||||||||||||||||||
| Granted (in shares) | 1,168,203 | 2,351,445 | 2,920,166 | 1,097,926 | 1,168,203 | 2,351,445 | ||||||||||||||||||||||||||||||
| Exercised (in shares) | (589,355) | (90,252) | 0 | |||||||||||||||||||||||||||||||||
| Forfeited, expired or cancelled (in shares) | (151,190) | (526,245) | (198,181) | |||||||||||||||||||||||||||||||||
| Outstanding at end of year (in shares) | 7,216,041 | 6,788,383 | 5,053,435 | |||||||||||||||||||||||||||||||||
| Exercisable at end of year (in shares) | 4,814,926 | 4,276,834 | 3,366,807 | |||||||||||||||||||||||||||||||||
| Stock options activity, weighted average exercise price [Roll Forward] | ||||||||||||||||||||||||||||||||||||
| Outstanding at beginning of year (in dollars per share) | $ 8.99 | [1] | $ 12.55 | [1] | $ 25.36 | [1] | ||||||||||||||||||||||||||||||
| Granted (in dollars per share) | $ 3.13 | [1] | $ 2.59 | [1] | $ 2.81 | [1] | ||||||||||||||||||||||||||||||
| Exercised (in dollars per share) | $ 2.26 | [1] | $ 1.68 | [1] | $ 0 | [1] | ||||||||||||||||||||||||||||||
| Forfeited, expired or cancelled (in dollars per share) | $ 17.46 | [1] | $ 15.84 | [1] | $ 35.56 | [1] | ||||||||||||||||||||||||||||||
| Outstanding at end of year (in dollars per share) | $ 8.42 | [1] | $ 8.99 | [1] | $ 12.55 | [1] | ||||||||||||||||||||||||||||||
| Exercisable at end of year (in dollars per share) | $ 11.14 | [1] | $ 12.42 | [1] | $ 16.33 | [1] | ||||||||||||||||||||||||||||||
| Stock options vested and expected to vest [Abstract] | ||||||||||||||||||||||||||||||||||||
| Options vested and expected to vest, number of shares (in shares) | 6,972,744 | |||||||||||||||||||||||||||||||||||
| Options vested and expected to vest, weighted-average exercise price (in dollars per share) | $ 8.61 | |||||||||||||||||||||||||||||||||||
| Additional disclosures [Abstract] | ||||||||||||||||||||||||||||||||||||
| Options outstanding, weighted average remaining contractual term | 6 years 6 months | |||||||||||||||||||||||||||||||||||
| Options outstanding, aggregate intrinsic value | 18,200,000 | |||||||||||||||||||||||||||||||||||
| Options exercisable, weighted average remaining contractual term | 5 years 7 months 6 days | |||||||||||||||||||||||||||||||||||
| Options exercisable, aggregate intrinsic value | 9,200,000 | |||||||||||||||||||||||||||||||||||
| Minimum age required for employees to qualify for immediate vesting of RSUs | 55 years | |||||||||||||||||||||||||||||||||||
| Threshold years required for retirement age | 70 years | |||||||||||||||||||||||||||||||||||
| Unvested RSU activity [Roll Forward] | ||||||||||||||||||||||||||||||||||||
| Unvested balance, beginning of period (in shares) | 1,459,853 | |||||||||||||||||||||||||||||||||||
| Granted (in shares) | 958,385 | 1,292,923 | 1,177,082 | |||||||||||||||||||||||||||||||||
| Vested (in shares) | (637,034) | |||||||||||||||||||||||||||||||||||
| Forfeited (in shares) | (43,167) | |||||||||||||||||||||||||||||||||||
| Unvested balance, end of period (in shares) | 1,738,037 | 1,459,853 | ||||||||||||||||||||||||||||||||||
| Unvested RSU activity, weighted average grant date fair value [Roll Forward] | ||||||||||||||||||||||||||||||||||||
| Unvested balance, beginning of period (in dollars per share) | $ 2.75 | |||||||||||||||||||||||||||||||||||
| Granted (in dollars per share) | $ 2.96 | |||||||||||||||||||||||||||||||||||
| Vested (in dollars per share) | $ 2.57 | |||||||||||||||||||||||||||||||||||
| Forfeited (in dollars per share) | $ 2.08 | |||||||||||||||||||||||||||||||||||
| Unvested balance, end of period (in dollars per share) | $ 2.73 | $ 2.75 | ||||||||||||||||||||||||||||||||||
| Total grant-date fair value of RSUs, vested | 958,385 | 1,600,000 | ||||||||||||||||||||||||||||||||||
| Stock-based awards weighted average assumptions [Abstract] | ||||||||||||||||||||||||||||||||||||
| Dividend yield (in hundredths) | 0.00% | 0.00% | 0.00% | |||||||||||||||||||||||||||||||||
| Expected volatility (in hundredths) | 92.00% | 92.00% | 88.00% | |||||||||||||||||||||||||||||||||
| Risk free interest rate (in hundredths) | 0.89% | 0.82% | 1.48% | |||||||||||||||||||||||||||||||||
| Expected term | 5 years 7 months 6 days | 5 years 7 months 6 days | 5 years 4 months 24 days | |||||||||||||||||||||||||||||||||
| Employee Service Share-based Compensation, Allocation of Recognized Period Costs [Line Items] | ||||||||||||||||||||||||||||||||||||
| Total stock-based compensation expense | 5,099,000 | 4,284,000 | 7,759,000 | 2,358,000 | 2,391,000 | 3,672,000 | 2,741,000 | 1,893,000 | 4,087,000 | |||||||||||||||||||||||||||
| Capitalized stock-based compensation cost | 0 | 0 | ||||||||||||||||||||||||||||||||||
| Tax benefits recognized related to stock-based compensation expense | $ 0 | $ 0 | ||||||||||||||||||||||||||||||||||
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