Quarterly report pursuant to Section 13 or 15(d)

Collaborative and Other Agreements - Servier - Additional Information (Details)

v3.5.0.2
Collaborative and Other Agreements - Servier - Additional Information (Details) - Collaborative Arrangement [Member] - Servier [Member] - USD ($)
3 Months Ended 6 Months Ended 9 Months Ended
Sep. 30, 2016
Sep. 30, 2015
Mar. 25, 2016
Sep. 30, 2016
Sep. 30, 2015
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]          
Future initial research and development expenses to be funded by counterparty       $ 50,000,000  
Contract and other revenue $ 0 $ 200,000   $ 300,000 $ 1,100,000
Deferred revenue recognized     $ 600,000