Quarterly report pursuant to Section 13 or 15(d)

Common Stock Warrants - Summary of Common Stock Warrants Outstanding (Details)

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Common Stock Warrants - Summary of Common Stock Warrants Outstanding (Details) - $ / shares
1 Months Ended 9 Months Ended
Feb. 29, 2016
Sep. 30, 2016
Dec. 31, 2015
Class Of Warrant Or Right [Line Items]      
Expiration Date 2021-02    
Exercise price of warrants (in dollars per share) $ 15.40    
Warrant outstanding (in shares)   916,547 908,298
Five Year Warrants Issued in December 2011 [Member] | Stockholders' Deficit [Member]      
Class Of Warrant Or Right [Line Items]      
Issuance Date   2011-12  
Expiration Date   2016-12  
Exercise price of warrants (in dollars per share)   $ 22.80  
Warrant outstanding (in shares)   13,158 13,158
Five Year Warrants Issued in March 2012 [Member] | Contingent Warrant Liabilities [Member]      
Class Of Warrant Or Right [Line Items]      
Issuance Date   2012-03  
Expiration Date   2017-03  
Exercise price of warrants (in dollars per share)   $ 35.20  
Warrant outstanding (in shares)   479,277 479,277
Five Year Warrants Issued in September 2012 [Member] | Stockholders' Deficit [Member]      
Class Of Warrant Or Right [Line Items]      
Issuance Date   2012-09  
Expiration Date   2017-09  
Exercise price of warrants (in dollars per share)   $ 70.80  
Warrant outstanding (in shares)   1,967 1,967
Two Year Warrants Issued in December 2014 [Member] | Contingent Warrant Liabilities [Member]      
Class Of Warrant Or Right [Line Items]      
Issuance Date   2014-12  
Expiration Date   2016-12  
Exercise price of warrants (in dollars per share)   $ 158.01  
Warrant outstanding (in shares)   404,833 404,833
Five Year Warrants Issued in February 2015 [Member] | Stockholders' Deficit [Member]      
Class Of Warrant Or Right [Line Items]      
Issuance Date   2015-02  
Expiration Date   2020-02  
Exercise price of warrants (in dollars per share)   $ 66.20  
Warrant outstanding (in shares)   9,063 9,063
Five Year Warrants Issued in February 2016 [Member] | Stockholders' Deficit [Member]      
Class Of Warrant Or Right [Line Items]      
Issuance Date   2016-02  
Expiration Date   2021-02  
Exercise price of warrants (in dollars per share)   $ 15.40  
Warrant outstanding (in shares)   8,249