Quarterly report pursuant to Section 13 or 15(d)

Collaborative, Licensing and Other Arrangements - Sale of Future Revenue Streams - Additional Information (Details)

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Collaborative, Licensing and Other Arrangements - Sale of Future Revenue Streams - Additional Information (Details)
$ in Thousands
 3 Months Ended
Dec. 21, 2016
USD ($)
Mar. 31, 2017
USD ($)
Agreement
Dec. 31, 2016
USD ($)
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]      
Deferred revenue – current   $ 1,381 $ 899 [1]
Deferred revenue, non-current   $ 17,408 18,000 [1]
HCRP [Member]      
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]      
Number of royalty Interest acquisition agreements | Agreement   2  
Deferred revenue   $ 18,000  
Contract and other revenue   100  
Deferred revenue – current   500  
Deferred revenue, non-current   $ 17,400 $ 18,000
HCRP [Member] | First Acquisition Agreement [Member]      
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]      
Upfront cash payment received $ 6,500    
Eligible potential additional payments receivable upon achievement of specified net sales milestones in 2017, 2018 and 2019 4,000    
HCRP [Member] | Second Acquisition Agreement [Member]      
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]      
Upfront cash payment received $ 11,500    
[1] The condensed consolidated balance sheet as of December 31, 2016 has been derived from the audited consolidated financial statements as of that date included in the Company’s Annual Report on Form 10-K for the year ended December 31, 2016.