Annual report pursuant to Section 13 and 15(d)

Collaborative, Licensing and Other Arrangements - NIAID - Additional Information (Details)

v3.6.0.2
Collaborative, Licensing and Other Arrangements - NIAID - Additional Information (Details) - USD ($)
 1 Months Ended 12 Months Ended
Oct. 31, 2011
Sep. 30, 2008
Dec. 31, 2016
Dec. 31, 2015
Dec. 31, 2014
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]          
Deferred revenue     $ 18,000,000    
Recognition of revenue     2,268,000 $ 6,383,000 $ 13,183,000
National Institute of Allergy and Infectious Diseases "NIAID" [Member] | Arrangement with Governmental Agency 2 [Member]          
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]          
Total contract amount awarded   $ 64,800,000      
Recognition of revenue     0 200,000 1,200,000
National Institute of Allergy and Infectious Diseases "NIAID" [Member] | Arrangement with Governmental Agency 3 [Member]          
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]          
Contractual term   3 years      
Increase (decrease) in deferred revenue         1,800,000
Deferred revenue         1,900,000
Remaining accounts receivable     400,000    
Remaining deferred revenue         100,000
National Institute of Allergy and Infectious Diseases "NIAID" [Member] | Arrangement with Governmental Agency 1 [Member]          
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]          
Total contract amount awarded $ 28,000,000        
Contractual term 5 years        
Recognition of revenue     $ 1,100,000 $ 4,900,000 $ 8,400,000