Annual report pursuant to Section 13 and 15(d)

Capital Stock - Common Stock Warrants - Additional Information (Details)

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Capital Stock - Common Stock Warrants - Additional Information (Details) - USD ($)
 1 Months Ended 12 Months Ended
Sep. 27, 2012
Feb. 29, 2016
Feb. 28, 2015
Sep. 30, 2012
Mar. 31, 2012
Dec. 31, 2011
Dec. 31, 2016
Dec. 31, 2014
Dec. 31, 2015
Dec. 08, 2014
Class Of Warrant Or Right [Line Items]                    
Aggregate number of unregistered shares of common stock called by warrants (in shares)   8,249                
Exercise price of warrants (in dollars per share)   $ 15.40                
Exercisable period of warrants   5 years                
Warrants expiration period   2021-02                
Estimated fair value of warrants   $ 100,000                
Warrant outstanding (in shares)             498,556   908,298  
GECC Term Loan [Member]                    
Class Of Warrant Or Right [Line Items]                    
Aggregate number of unregistered shares of common stock called by warrants (in shares) 1,967         13,158        
Exercise price of warrants (in dollars per share) $ 70.80         $ 22.80        
Exercisable period of warrants 5 years         5 years        
Estimated fair value of warrants $ 100,000         $ 200,000        
Five Year Warrants Issued in February 2015 [Member] | Hercules Loan [Member]                    
Class Of Warrant Or Right [Line Items]                    
Aggregate number of unregistered shares of common stock called by warrants (in shares)     9,063              
Exercise price of warrants (in dollars per share)     $ 66.20              
Exercisable period of warrants     5 years              
Two Year Warrants Issued in December 2014 [Member]                    
Class Of Warrant Or Right [Line Items]                    
Exercise price of warrants (in dollars per share)               $ 158.01    
Estimated fair value of warrants                 $ 3,000,000 $ 10,300,000
Warrant term               2 years    
Warrant outstanding (in shares)               404,833    
December 2014 Revalued Warrants [Member]                    
Class Of Warrant Or Right [Line Items]                    
Gain (loss) on revaluation of warrant liability             $ 3,000,000      
Five Year Warrants Issued in September 2012 [Member] | GECC Term Loan [Member]                    
Class Of Warrant Or Right [Line Items]                    
Aggregate number of unregistered shares of common stock called by warrants (in shares)       1,967            
Exercise price of warrants (in dollars per share)       $ 70.80            
Exercisable period of warrants       5 years            
Five Year Warrants Issued in March 2012 [Member]                    
Class Of Warrant Or Right [Line Items]                    
Exercise price of warrants (in dollars per share)         $ 35.20          
Estimated fair value of warrants             $ 0   $ 7,500,000  
Warrant term         5 years          
Warrant outstanding (in shares)         741,729   479,277   479,277  
March 2012 Revalued Warrants [Member]                    
Class Of Warrant Or Right [Line Items]                    
Gain (loss) on revaluation of warrant liability             $ 7,500,000