Annual report pursuant to Section 13 and 15(d)

CONSOLIDATED STATEMENTS OF STOCKHOLDERS' EQUITY (DEFICIT)

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CONSOLIDATED STATEMENTS OF STOCKHOLDERS' EQUITY (DEFICIT) - USD ($)
shares in Thousands, $ in Thousands
Total
Convertible Preferred Stock [Member]
Common Stock [Member]
Additional Paid-In Capital [Member]
Accumulated Deficit [Member]
Balance at Dec. 31, 2014 $ 3,099   $ 44 $ 1,122,532 $ (1,119,477)
Balance (in shares) at Dec. 31, 2014     5,795    
Increase (Decrease) in Stockholders' Equity [Roll Forward]          
Exercise of stock options and issuance of common stock, contributions to 401(k) and ESPP 1,467     1,467  
Exercise of stock options and issuance of common stock, contributions to 401(k) and ESPP (in shares)     27    
Vesting of restricted stock units (in shares)     60    
Stock-based compensation expense 9,727     9,727  
Issuance of warrants 450     450  
Exercise of warrants 3,554   $ 1 3,553  
Exercise of warrants (in shares)     70    
Net income (loss) and comprehensive income (loss) (20,606)       (20,606)
Balance at Dec. 31, 2015 (2,309)   $ 45 1,137,729 (1,140,083)
Balance (in shares) at Dec. 31, 2015     5,952    
Increase (Decrease) in Stockholders' Equity [Roll Forward]          
Exercise of stock options and issuance of common stock, contributions to 401(k) and ESPP 844     844  
Exercise of stock options and issuance of common stock, contributions to 401(k) and ESPP (in shares)     36    
Vesting of restricted stock units     $ 1 (1)  
Vesting of restricted stock units (in shares)     113    
Stock-based compensation expense 7,645     7,645  
Issuance of warrants 97     97  
Issuance of common stock 43     43  
Issuance of common stock (in shares)     13    
Net income (loss) and comprehensive income (loss) (53,530)       (53,530)
Balance at Dec. 31, 2016 (47,210)   $ 46 1,146,357 (1,193,613)
Balance (in shares) at Dec. 31, 2016     6,114    
Increase (Decrease) in Stockholders' Equity [Roll Forward]          
Cumulative effect adjustment to accumulated deficit due to adoption of ASU 2016-09       42 (42)
Exercise of stock options 658   $ 1 657  
Exercise of stock options (in shares)     110    
Exercise of stock options and issuance of common stock, contributions to 401(k) and ESPP 532   $ 1 531  
Exercise of stock options and issuance of common stock, contributions to 401(k) and ESPP (in shares)     102    
Vesting of restricted stock units     $ 1 (1)  
Vesting of restricted stock units (in shares)     74    
Stock-based compensation expense 7,301     7,301  
Issuance of convertible preferred stock 20,019     20,019  
Issuance of convertible preferred stock (in shares)   5      
Issuance of common stock 9,890   $ 13 9,877  
Issuance of common stock (in shares)     1,849    
Net income (loss) and comprehensive income (loss) 14,596       14,596
Balance at Dec. 31, 2017 $ 5,786   $ 62 $ 1,184,783 $ (1,179,059)
Balance (in shares) at Dec. 31, 2017   5 8,249