Annual report pursuant to Section 13 and 15(d)

Capital Stock - Summary of Common Stock Warrants Outstanding (Details)

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Capital Stock - Summary of Common Stock Warrants Outstanding (Details) - $ / shares
1 Months Ended 12 Months Ended
Feb. 29, 2016
Dec. 31, 2017
Dec. 31, 2016
Mar. 31, 2012
Class Of Warrant Or Right [Line Items]        
Expiration Date 2021-02      
Exercise price of warrants (in dollars per share) $ 15.40      
Number of Shares   17,312 498,556  
Five Year Warrants Issued in March 2012 [Member]        
Class Of Warrant Or Right [Line Items]        
Exercise price of warrants (in dollars per share)       $ 35.20
Five Year Warrants Issued in March 2012 [Member] | Contingent Warrant Liability [Member]        
Class Of Warrant Or Right [Line Items]        
Issuance Date   2012-03    
Expiration Date   2017-03    
Exercise price of warrants (in dollars per share)   $ 35.20    
Number of Shares     479,277  
Five Year Warrants Issued in September 2012 [Member] | Stockholders' Equity (Deficit) [Member]        
Class Of Warrant Or Right [Line Items]        
Issuance Date   2012-09    
Expiration Date   2017-09    
Exercise price of warrants (in dollars per share)   $ 70.80    
Number of Shares     1,967  
Five Year Warrants Issued in February 2015 [Member] | Stockholders' Equity (Deficit) [Member]        
Class Of Warrant Or Right [Line Items]        
Issuance Date   2015-02    
Expiration Date   2020-02    
Exercise price of warrants (in dollars per share)   $ 66.20    
Number of Shares   9,063 9,063  
Five Year Warrants Issued in February 2016 [Member] | Stockholders' Equity (Deficit) [Member]        
Class Of Warrant Or Right [Line Items]        
Issuance Date   2016-02    
Expiration Date   2021-02    
Exercise price of warrants (in dollars per share)   $ 15.40    
Number of Shares   8,249 8,249