Annual report pursuant to Section 13 and 15(d)

Description of Business - Additional Information (Details)

v3.6.0.2
Description of Business - Additional Information (Details)
$ / shares in Units, $ in Thousands
1 Months Ended 12 Months Ended
Feb. 28, 2017
USD ($)
Oct. 31, 2016
$ / shares
Dec. 31, 2016
USD ($)
$ / shares
Dec. 31, 2015
USD ($)
$ / shares
Dec. 31, 2014
USD ($)
Dec. 31, 2013
USD ($)
Description Of Business [Line Items]            
Accumulated deficit     $ (1,193,613) $ (1,140,083)    
Working capital deficiency     5,300      
Carrying value of the loan     43,167 48,667    
Cash and cash equivalents     $ 25,742 $ 65,767 $ 78,445 $ 101,659
Reverse stock split, description     In October 2016, the Company’s stockholders voted at a special meeting of stock holders to approve a series of alternate amendments to the Company’s Amended Certificate of Incorporation to effect a reverse stock split of the Company’s issued and outstanding common stock. The Company’s Board of Directors then approved a specific reverse split ratio of 1-for-20.      
Reverse stock split ratio   0.05        
Common stock, par value per share | $ / shares   $ 0.0075 $ 0.0075 $ 0.0075    
Preferred stock, par value per share | $ / shares   $ 0.05 $ 0.05 $ 0.05    
Subsequent Event [Member]            
Description Of Business [Line Items]            
Net proceeds from registered direct offering $ 24,900