Annual report pursuant to Section 13 and 15(d)

Net Loss per Share of Common Stock - Reconciliation of the Numerators and Denominators Used in Calculating Basic and Diluted Net Loss per Share of Common Stock (Details)

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Net Loss per Share of Common Stock - Reconciliation of the Numerators and Denominators Used in Calculating Basic and Diluted Net Loss per Share of Common Stock (Details) - USD ($)
$ / shares in Units, shares in Thousands, $ in Thousands
 3 Months Ended 12 Months Ended
Dec. 31, 2016
Sep. 30, 2016
Jun. 30, 2016
Mar. 31, 2016
Dec. 31, 2015
Sep. 30, 2015
Jun. 30, 2015
Mar. 31, 2015
Dec. 31, 2016
Dec. 31, 2015
Dec. 31, 2014
Numerator                      
Net loss, basic                 $ (53,530) $ (20,606) $ (38,301)
Adjustment for revaluation of contingent warrant liabilities                     (39,512)
Net loss, diluted                 $ (53,530) $ (20,606) $ (77,813)
Denominator                      
Weighted average shares outstanding used for basic net loss per share (in shares)                 6,021 5,890 5,372
Effect of dilutive warrants (in shares)                     395
Weighted average shares outstanding and dilutive securities used for diluted net loss per share (in shares)                 6,021 5,890 5,767
Basic net loss per share of common stock (in dollars per share) $ (2.89) $ (2.10) $ (2.57) $ (1.45) $ 4.27 $ (0.08) $ (4.04) $ (3.74) $ (8.89) $ (3.50) $ (7.13)
Diluted net loss per share of common stock (in dollars per share) $ (2.89) $ (2.10) $ (2.57) $ (1.45) $ 4.24 [1] $ (0.08) [1] $ (4.04) [1] $ (3.74) [1] $ (8.89) $ (3.50) $ (13.49)
[1] For the quarter ended December 31, 2015, the Company’s diluted net income per share of common stock was computed by giving effect to all potentially dilutive common stock equivalents outstanding during the period.