Compensation and Other Benefit Plans - Stock-based Compensation Expense (Details) - USD ($) $ in Thousands |
12 Months Ended | ||
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Dec. 31, 2016 |
Dec. 31, 2015 |
Dec. 31, 2014 |
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| Employee Service Share-based Compensation, Allocation of Recognized Period Costs [Line Items] | |||
| Total stock-based compensation expense | $ 7,645 | $ 9,727 | $ 10,772 |
| Research and Development [Member] | |||
| Employee Service Share-based Compensation, Allocation of Recognized Period Costs [Line Items] | |||
| Total stock-based compensation expense | 2,805 | 5,022 | 5,557 |
| Selling, General and Administrative [Member] | |||
| Employee Service Share-based Compensation, Allocation of Recognized Period Costs [Line Items] | |||
| Total stock-based compensation expense | 4,221 | $ 4,705 | $ 5,215 |
| Restructuring [Member] | |||
| Employee Service Share-based Compensation, Allocation of Recognized Period Costs [Line Items] | |||
| Total stock-based compensation expense | $ 619 | ||
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- Definition Represents the expense recognized during the period arising from equity-based compensation arrangements (for example, shares of stock, unit, stock options or other equity instruments) with employees, directors and certain consultants qualifying for treatment as employees. Reference 1: http://www.xbrl.org/2003/role/presentationRef
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- Definition Line items represent financial concepts included in a table. These concepts are used to disclose reportable information associated with domain members defined in one or many axes to the table. No definition available.
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