Annual report pursuant to Section 13 and 15(d)

Fair Value Measurements - Outstanding Debt Carrying Amount and Estimated Fair Value (Details)

v3.6.0.2
Fair Value Measurements - Outstanding Debt Carrying Amount and Estimated Fair Value (Details) - USD ($)
$ in Thousands
Dec. 31, 2016
Dec. 31, 2015
Fair Value, Balance Sheet Grouping, Financial Statement Captions [Line Items]    
Interest-bearing obligations, Carrying Amount $ 43,167 $ 48,667
Interest bearing obligations, Fair Value 42,531 49,810
Hercules Term Loan [Member]    
Fair Value, Balance Sheet Grouping, Financial Statement Captions [Line Items]    
Interest-bearing obligations, Carrying Amount 16,850 19,653
Interest bearing obligations, Fair Value 16,453 21,231
Servier Loan [Member]    
Fair Value, Balance Sheet Grouping, Financial Statement Captions [Line Items]    
Interest-bearing obligations, Carrying Amount 12,231 15,331
Interest bearing obligations, Fair Value 12,242 15,185
Novartis Note [Member]    
Fair Value, Balance Sheet Grouping, Financial Statement Captions [Line Items]    
Interest-bearing obligations, Carrying Amount 14,086 13,683
Interest bearing obligations, Fair Value $ 13,836 $ 13,394