Quarterly report pursuant to Section 13 or 15(d)

Common Stock Warrants - Summary of Common Stock Warrants Outstanding (Details)

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Common Stock Warrants - Summary of Common Stock Warrants Outstanding (Details) - $ / shares
 6 Months Ended
Jun. 30, 2017
Dec. 31, 2016
Mar. 31, 2012
Class Of Warrant Or Right [Line Items]      
Warrant outstanding (in shares) 19,279 498,556  
Five Year Warrants Issued in March 2012 [Member]      
Class Of Warrant Or Right [Line Items]      
Exercise price of warrants (in dollars per share)     $ 35.20
Five Year Warrants Issued in March 2012 [Member] | Contingent Warrant Liability [Member]      
Class Of Warrant Or Right [Line Items]      
Issuance Date 2012-03    
Expiration Date 2017-03    
Exercise price of warrants (in dollars per share) $ 35.20    
Warrant outstanding (in shares)   479,277  
Five Year Warrants Issued in September 2012 [Member] | Stockholders' Deficit [Member]      
Class Of Warrant Or Right [Line Items]      
Issuance Date 2012-09    
Expiration Date 2017-09    
Exercise price of warrants (in dollars per share) $ 70.80    
Warrant outstanding (in shares) 1,967 1,967  
Five Year Warrants Issued in February 2015 [Member] | Stockholders' Deficit [Member]      
Class Of Warrant Or Right [Line Items]      
Issuance Date 2015-02    
Expiration Date 2020-02    
Exercise price of warrants (in dollars per share) $ 66.20    
Warrant outstanding (in shares) 9,063 9,063  
Five Year Warrants Issued in February 2016 [Member] | Stockholders' Deficit [Member]      
Class Of Warrant Or Right [Line Items]      
Issuance Date 2016-02    
Expiration Date 2021-02    
Exercise price of warrants (in dollars per share) $ 15.40    
Warrant outstanding (in shares) 8,249 8,249